Projects
Welcome to my projects! Here, I showcase my journey in translational research and drug discovery. You can explore my contributions to precision medicine, biomarker development, and preclinical oncology models.
Development of Epigenetic Biomarkers and Diagnostic Platforms
Principal Scientist
As Principal Scientist at Episteme Prognostics, I drive biomarker discovery and clinical translation through ATAC-array optimization for cancer diagnostics. I lead assay design, validation, and multi-omic integration, while implementing Six Sigma quality systems and CLIA-compliant SOPs, bridging discovery biology, assay engineering, and regulatory readiness to deliver scalable diagnostic solutions.
Enhancing Epigenetic and Immunotherapy Efficacy in PDAC
Senior Research Scientist
I developed and applied advanced experimental systems to interrogate PDAC biology and treatment response. Through integrated immune characterization, functional assays, and pathway-level transcriptomic analysis, the project uncovered novel therapeutic targets and offered translational insights for designing more effective preclinical strategies in epigenetic and immune-based interventions.
CTLH complex in NSCLC
Post Doctoral Researcher
I uncovered how RANBP9 and RANBP10, paralogous scaffolds of the CTLH E3 ligase, cooperate yet antagonize to regulate non-small cell lung cancer proliferation. Through CRISPR-engineered models, proteomics, and patient data, we demonstrated their ratio functions as a rheostat, linking ubiquitylation dynamics to oncogenic growth
Identification of new therapeutic targets in analplastic thyroid cancer
Research Fellow
I led a target discovery program in anaplastic thyroid cancer, identifying AGC kinases as key oncogenic drivers within the PI3K pathway. By developing 30+ cellular models and optimizing functional assays, I enabled >100 drug studies, advancing mechanistic insights and therapeutic strategies for ATC.
Role of iws1 gene in mouse development
Post Doctoral Researcher
Through functional in vivo studies, I identified IWS1 as a critical RNAPII elongation factor whose deletion results in early embryonic lethality. Mechanistic work highlighted IWS1’s role in transcriptional elongation and chromatin modification, positioning it as a key regulator of developmental epigenetics.